The Contact Allergen Database

What is The Contact Allergen Database?

The contact allergen database is an on-line accessible database providing clinical information on substances that have caused allergic contact dermatitis as proven by patch testing. All information will be fully referenced, so that additional or more detailed information - if required - can be looked up in the referenced (original) articles.

This database will be different from virtually all textbooks in the field of contact dermatitis in the sense that the point of entry (the subject) is always a chemical. Each reported contact allergen will have a separate file with a standardized structure. On the opening page of each file the following information will be provided.

  • Name
  • Merck Index Name
  • INCI Name (International Nomenclature Cosmetic Ingredient)
  • RIFM Name (Research Institute for Fragrance Materials)
  • Other Synonyms
  • CAS Registry Number
  • EINECS Number
  • Chemical Formula
  • Structural Formula
  • Category

In addition, the opening page shows links to the following categories of information presented in sub pages:

  • Presence/applications
  • Sensitization experiments
  • Contact allergy
  • Irritant contact dermatitis
  • Photosensitivity
  • Immediate contact reactions
  • Other non-eczematous contact reactions
  • Patch test sensitization
  • Systemic side effects
  • Miscellaneous side effects
  • Commercial availability
  • Other information
  • Pertinent literature not yet reviewed

Search possibilities

There are three search strategies:

1. by name or part of a name, including an asterisk function. All name fields (Name, Merck Index Name, INCI Name, RIFM Name, Other Synonyms) will be searched for the query.
2. by CAS Registry Number
3. by letter with which your search term begins

Where does the database information come from en when will it be operational and accessible?

At this time (August 2008) the infrastructure (software) is being developed. As soon as it is operational, relevant information will be implemented. We will start with the 2008 issues of the journal Contact Dermatitis and work our way back, but also implement newly published issues. Next are Dermatitis, American Journal of Contact Dermatitis and Dermatosen in Beruf und Umwelt, followed by other relevant journals and possibly textbooks.

At this stage, it is not possible to estimate how fast the project may develop and when it will contain enough information to be worthwhile for dermatologists and other interested parties to consult the database.

Interested in the development of the database?

If you are interested in this project, please indicate on the home page that you want to receive the newsletter and we will keep you fully informed on the progress and when you can access the contact allergen database.